The aim of this study was to compare the effectiveness of cognitive behavior therapy (CBT) and metacognitive therapy (MCT) on reducing anxiety and worry in persons with generalized anxiety disorder (GAD). The sample consisted of 25 persons with GAD who were randomly assigned to two groups: CBT and MCT. The MCT manual for anxiety has 10 ses-sions and the CBT manual for anxiety has 9 sessions. In this study the participants received 45-60 minutes individual therapy sessions twice per week. They also completed Beck Anxiety Inventory (BAI) and Pennsylvania State Worry Questionnaire (PSWQ) pre-test and post-test. The results indicated that metacognitive therapy was more effective than cognitive behavior the-rapy in decreasing anxiety and worry (P<0.05); However, compared to cognitive behavioral the -rapy, metacognitive therapy, was clinically more effective in reducing worry only.